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Novel Schiff Base Co(II) Complexes: Potential Biological Applications
Arumugam Parasuraman Arumugam 1, Govindan Elango 1 and Selvam Guhanathan 2*
1Department of Chemistry, Kalaignar Karunanidhi Government. Arts College, Tiruvannamalai, Tamil Nadu., India
2Department of Chemistry, Muthurangam Government Arts College (Autonomous), Vellore, Tamilnadu., India
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Abstract:
Cobalt (Co) complexes with the N2O2 category have been created synthetically by the reaction of salicylaldehyde / 3,4-diamino benzophenone with acetylacetone and glutaric anhydride respectively. The ligands and individual Cobalt (II) complexes were recognized through spectroscopical data (Fourier Transform Infrared, Ultra Violet-visible, proton and carbon-13 NMR, & Mass). Non-electrolytic in nature of the complex found from their molar conductivities (Ω-1cm2mol-1) in DMSO of 10-3M solution. The ESR revealed the geometry of the complexes to be octahedral. The Schiff base Cobalt (II) complex was characterized by anticancer activity and cytotoxicity
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Keywords: Glutaric anhydride Anticancer activity, Cytotoxicity, Morphological study
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Received:August 22, 2022; Revised:September 12, 2022; Accepted:September 22, 2022; Published:September 30, 2022
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*Corresponding author; e-mail: sai_gugan@yahoo.com
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Citation:Parasuraman, A.; Elango, G.; Guhanathan, S.Novel Schiff Base Co(II) Complexes: Potential Biological Applications. Applied Functional Materials 2022, 2, 42-50. https://doi.org/10.35745/afm2022v02.03.0006
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Copyright: ©
2022
The Author(s). Published with license by IIKII, Singapore. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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